KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYNC1LI1
All Species:
20.61
Human Site:
T508
Identified Species:
41.21
UniProt:
Q9Y6G9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6G9
NP_057225.2
523
56579
T508
R
I
T
R
K
P
V
T
V
S
P
T
T
P
T
Chimpanzee
Pan troglodytes
XP_001167584
472
51615
T457
R
I
T
R
K
P
V
T
V
S
P
T
T
P
T
Rhesus Macaque
Macaca mulatta
XP_001085468
497
54504
T481
Q
E
E
L
D
R
M
T
R
K
P
D
S
M
V
Dog
Lupus familis
XP_534236
524
56481
T509
R
I
A
R
K
P
V
T
V
S
P
A
A
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1Q8
523
56596
S508
R
I
T
R
K
P
A
S
V
S
P
T
T
P
T
Rat
Rattus norvegicus
Q9QXU8
523
56774
S508
R
I
T
R
K
P
A
S
V
S
P
T
T
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508928
471
51509
M456
R
I
S
R
K
P
D
M
V
S
P
T
T
P
T
Chicken
Gallus gallus
Q90828
515
55875
M500
R
I
S
R
K
P
E
M
V
S
P
T
S
P
T
Frog
Xenopus laevis
NP_001082059
508
56047
I493
R
I
S
R
K
P
D
I
V
S
P
T
S
P
T
Zebra Danio
Brachydanio rerio
NP_001017669
498
54667
S484
R
M
T
R
K
P
D
S
L
V
T
A
N
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395283
470
52288
D455
K
I
D
S
A
S
V
D
K
A
T
M
C
N
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795494
483
53698
G469
E
L
D
R
M
T
R
G
R
K
P
V
A
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
60.7
96.3
N.A.
94.6
94.4
N.A.
82.4
86.4
79.7
64.4
N.A.
N.A.
45.1
N.A.
47.4
Protein Similarity:
100
88.9
73.8
97.7
N.A.
96.7
96.7
N.A.
85.8
91.7
88.9
76.6
N.A.
N.A.
60.7
N.A.
64.4
P-Site Identity:
100
100
13.3
80
N.A.
86.6
80
N.A.
80
73.3
73.3
40
N.A.
N.A.
13.3
N.A.
20
P-Site Similarity:
100
100
33.3
80
N.A.
93.3
86.6
N.A.
86.6
86.6
86.6
60
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
17
0
0
9
0
17
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
17
0
9
0
25
9
0
0
0
9
0
0
9
% D
% Glu:
9
9
9
0
0
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
75
0
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
0
75
0
0
0
9
17
0
0
0
0
0
% K
% Leu:
0
9
0
9
0
0
0
0
9
0
0
0
0
0
0
% L
% Met:
0
9
0
0
9
0
9
17
0
0
0
9
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
17
0
% N
% Pro:
0
0
0
0
0
75
0
0
0
0
84
0
0
67
9
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
75
0
0
84
0
9
9
0
17
0
0
0
0
0
0
% R
% Ser:
0
0
25
9
0
9
0
25
0
67
0
0
25
0
0
% S
% Thr:
0
0
42
0
0
9
0
34
0
0
17
59
42
0
75
% T
% Val:
0
0
0
0
0
0
34
0
67
9
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _